Dupuytren contracture

Overview

Dupuytren contracture is a condition characterized by the bending of one or more fingers toward the palm of the hand, making it difficult for the affected fingers to fully extend. This condition is marked by the development of knots of tissue beneath the skin, which eventually form a thick cord that can cause the fingers to bend. As time passes, Dupuytren contracture tends to worsen progressively.

Symptoms

Dupuytren contracture is a condition that progresses gradually over time. The initial symptom is the development of a firm lump in the palm of the hand, which may or may not be painful. As the condition advances, this lump can extend into a tough cord beneath the skin and into the finger. This cord often tightens and pulls the affected finger toward the palm. Typically, Dupuytren contracture primarily affects the two fingers farthest from the thumb, and it commonly affects both hands.

Causes

It is uncertain what causes Dupuytren contracture. The illness typically runs in families. Men are more likely than women to have it.

Risk factors

The following are risk factors for Dupuytren contracture:

• Age. The most prevalent age at which Dupuytren contracture arises is after 50.
• Gender. Dupuytren is far more common in men than in women. Men may experience worsening symptoms that worsen faster.
• Race. Individuals with ancestry from Northern Europe are more susceptible to the illness.
• Family history. Oftentimes, Dupuytren contracture runs in families.
• Occupation. Research indicates a link between vibrating tool users and Dupuytren contracture.
• Diabetes. Diabetes increases the chance of Dupuytren contracture.
• Tobacco and alcohol use. The risk of Dupuytren contracture is increased by both alcohol consumption and tobacco use
• Other medical conditions. Having epilepsy and other seizure disorders, alcohol use disorder (also known as alcoholism), HIV and AIDS, or vascular disease.